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Endovascular surgery involves minimally invasive procedures that use catheters to deliver therapy and devices to patients with vascular diseases. The demand for endovascular therapies continues to grow dramatically with the global trend towards minimally invasive surgery.

While beneficial, these procedures expose patients and health caregivers to harmful levels of radiation due to the use of X-ray fluoroscopy for navigating through the vascular system.  IOPS addresses these challenges by using safe electromagnetic tracking, while improving navigation and simplifying complex procedures.

Outside of the development of our IOPS device, we’re excited to see other advancements in endovascular surgery. Below, you’ll find relevant articles, as well as Centerline Biomedical press releases, to keep you up-to-date on the world of endovascular surgery innovations.


Press Releases


TechOhio Founder Story: Centerline Biomedical Image

TechOhio Founder Story: Centerline Biomedical

June 18, 2018 -- Vascular disease is increasingly common, affecting millions of people in the U.S. Procedures to address vascular conditions are complex, risky and potentially harmful to patients—and even to the physicians who treat them. That’s why Centerline Biomedical in Cleveland is developing an innovative system to help physicians navigate catheters, guidewires and devices in the 3D anatomy of vascular disease patients. Centerline’s advanced visualization and navigation tools empower surgeons to perform safer, more accurate and more efficient endovascular procedures. The company, a Cleveland Clinic spinoff, operates with continued support from Ohio Third Frontier and its partners, including the Global Cardiovascular Innovation Center, where the company is located.

Wall Street Journal: Cleveland Clinic spinoff is at the center of efforts to remake the operating room Image

Wall Street Journal: Cleveland Clinic spinoff is at the center of efforts to remake the operating room

May 28, 2018 -- Centerline Biomedical, a Cleveland Clinic spinoff, is part of this Wall Street Journal story about tech advances that are making the operating room "smarter, more effective — and a lot less risky for patients." 

 

Crain's Cleveland Business: HoloLens technology offers opportunity for Cleveland Clinic spinoff Image

Crain's Cleveland Business: HoloLens technology offers opportunity for Cleveland Clinic spinoff

April 22, 2018 -- New technology being explored in Cleveland could give surgeons close to X-ray vision.

Cleveland-based surgical navigation startup Centerline Biomedical has for years been working to develop its Intra-Operative Positioning System (IOPS), a GPS-like system that provides 3D guidance during minimally invasive procedures.

Surgeons would have to look at a monitor to follow the guidance, but a new grant is offering Centerline and Cleveland Clinic researcher Karl West the chance to add HoloLens, a mixed-reality device from Microsoft, to the experience.


Centerline Biomedical Completes Fifth Preclinical Study Image

Centerline Biomedical Completes Fifth Preclinical Study

January 2, 2018 -- Endovascular navigation startup demonstrates use of navigation system 

Cleveland, Ohio: As Centerline Biomedical, Inc. prepares to meet with investors, strategic partners and companies in the healthcare industry during the JP Morgan Healthcare Conference, it successfully completed a fifth preclinical study at Cleveland Clinic facilities evaluating its surgical navigation system, IOPS, the Intra-Operative Positioning System. This study was the most noteworthy Centerline study to date, demonstrating ability to track sensorized IOPS instruments precisely and efficiently, with enhanced 3-D visualization, without frequent exposure to cancer-causing ionizing radiation associated with current standard of care.

Centerline Biomedical Named MedTech Innovator Top 50 Showcase Company Image

Centerline Biomedical Named MedTech Innovator Top 50 Showcase Company

May 31, 2017 -- ​We are proud to announce that Centerline Biomedical has been chosen as a MedTech Innovator Top 50 showcase company! The 50 companies were chosen from nearly 600 applicants to the 2017 MedTech Innovator competition. These top companies will present during 11 interactive sessions on a special stage at the MedTech Innovator Showcase, an exhibition of the cutting-edge innovations to be presented at The MedTech Conference Sept. 25 to 27 in San Jose, California.

Centerline Biomedical Furthers Funding Goals with $1.26M Ohio Third Frontier Funding Image

Centerline Biomedical Furthers Funding Goals with $1.26M Ohio Third Frontier Funding

Endovascular navigation startup receives economic development funding 

Cleveland, Ohio: We are proud to announce that, on March 29th, 2017, Centerline Biomedical, Inc. was approved by the Ohio Third Frontier Commission for a $1.26M Commercial Acceleration Loan Fund (CALF), under the Ohio Third Frontier Program, managed by the State of Ohio’s Development Services Agency (DSA). 

Centerline Biomedical Rounds Up Successful Year With Series A Fundraising Image

Centerline Biomedical Rounds Up Successful Year With Series A Fundraising

Endovascular navigation startup continues to build momentum with development and funding milestones

Cleveland, Ohio: Surgical navigation startup Centerline Biomedical, Inc. closed a Series A funding round in December 2016. This significant milestone comes on the heels of several preclinical studies and builds upon successful financing and outreach achieved over the course of 2016, driving the company forward in its commercialization mission.

Centerline Biomedical Successfully Completes Next Set of Preclinical Studies Image

Centerline Biomedical Successfully Completes Next Set of Preclinical Studies

Cleveland, Ohio: Building on a study performed in May, Centerline Biomedical, Inc. successfully completed two additional preclinical studies evaluating its advanced surgical navigation system known as IOPS, the Intra-Operative Positioning System. The studies demonstrated the ability to track navigation of catheters and guidewires precisely, with enhanced 3-D visualization, and without the harmful effects associated with the current standard of care.


Centerline Biomedical Successfully Completes First Preclinical Study Image

Centerline Biomedical Successfully Completes First Preclinical Study

Endovascular Navigation Innovator Centerline Biomedical Successfully Completes First Preclinical Study
In vivo study bolsters commercialization efforts

Cleveland, Ohio: Centerline Biomedical, a Cleveland Clinic spinoff company, successfully completed its first preclinical study evaluating its innovative endovascular navigation technology, IOPS, at the world-renowned Lerner Research Institute on Monday, May 2nd.

Additional Articles


HoloLens technology offers opportunity for Centerline Biomedical Image

HoloLens technology offers opportunity for Centerline Biomedical

A new grant gives Centerline the opportunity to use HoloLens, a mixed-reality device from Microsoft, as an additional tool to be used alongside IOPS.  The HoloLens helps the surgeon visualize the patient's anatomy, increasing visibility and navigation.  Karl West described it by saying, "It's like having X-ray vision."


Gearing Up to Enter the Market in 2017 Image

Gearing Up to Enter the Market in 2017

The Centerline Biomedical team is excited to continue work gearing up for market entry!
Our innovative IOPS (Intra-Operative Positioning System) device, which provides 3D guidance for endovascular surgery, will allow surgeons to navigate a patient’s arteries in greater detail and with more accuracy than what is offered by the current standard of care.
 
Learn more about our history and the inspiration behind the IOPS device in this article.

CX Acknowledges

CX Acknowledges "huge debt" owed to endovascular pioneers affected by radiation

Since its introduction in the late 80s, endovascular therapy has become increasingly widespread and important. A mini-symposium held at the 2016 Charing Cross Symposium (26-29 April, London, UK), brought to the fore the radiation damage that has occurred to pioneering operators in the field. It also focused on currently available methods to reduce radiation exposure during endovascular procedures. 

Do-Better or Do-Over? Cath Lab Safety May Be Ready for a Reboot Image

Do-Better or Do-Over? Cath Lab Safety May Be Ready for a Reboot

At the 2015 Society for Cardiovascular Angiography and Interventions Scientific Sessions, Jonathan J. Rome, MD, director of the catheterization laboratories at The Children’s Hospital of Philadelphia, discussed an issue that affects all interventional cardiologists and radiologists: the long-term toll on our bodies resulting from lifetime exposure to radiation and wearing protective equipment.


Watch 6-minute Documentary on Fluoroscopic Radiation Risks Image

Watch 6-minute Documentary on Fluoroscopic Radiation Risks

This video tells the story of one of the world’s most prominent cardiovascular surgeons, Dr. Edward Diethrich, and the career-altering health issues he has faced as a result of chronic, low-level exposure to ionizing radiation through his work.
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